
This article details a recent experiment that demonstrates how nonspecific interactions can be prevented by using metal-free or low adsorption flow paths.
Sonja Schneider is manager, Applications Development at Agilent Technologies. She has led the application development team in Waldbronn, Germany, since 2016.

This article details a recent experiment that demonstrates how nonspecific interactions can be prevented by using metal-free or low adsorption flow paths.

This application note demonstrates the analysis of charge variants of Rituximab (both innovator and biosimilar molecules) using multiple heart-cutting two-dimensional liquid chromatography (2D-LC) with mass spectrometry (MS) detection.


This Application Note demonstrate ultrafast gradients with an over 60 % reduction of analysis time using the Agilent 1290 Infinity II Multisampler with dual-needle function and alternating column regeneration.

This Application Note demonstrate ultrafast gradients with an over 60 % reduction of analysis time using the Agilent 1290 Infinity II Multisampler with dual-needle function and alternating column regeneration.

Agilent Intelligent System Emulation technology (ISET) in the Agilent 1290 Infinity II LC facilitates the transfer of methods from conventional HPLC systems such as the Agilent 1100 Series Binary LC. This Application Note illustrates the advantages of ISET for the analysis of six tricyclic antidepressants.

Agilent Intelligent System Emulation technology (ISET) in the Agilent 1290 Infinity II LC facilitates the transfer of methods from conventional HPLC systems such as the Agilent 1100 Series Binary LC. This Application Note illustrates the advantages of ISET for the analysis of six tricyclic antidepressants.

This Application Note shows the transfer of an analysis method for anti-epileptic drugs from HPLC to UHPLC using the Agilent 1290 Infinity II LC system. An enormous time and solvent saving of approximately 95 % was achieved with an UHPLC separation optimized for speed.

The Agilent 1290 Infinity II High Dynamic Range Diode Array Detection Impurity Analyzer Solution combines the signals from two diode array detectors with different path length Max-Light cartridge cells to increase the linear dynamic UV-range. This solution can be used to detect and quantify main and trace compounds in a single run without exceeding the linear UV-range.

This Application Note shows the transfer of an analysis method for anti-epileptic drugs from HPLC to UHPLC using the Agilent 1290 Infinity II LC system. An enormous time and solvent saving of approximately 95 % was achieved with an UHPLC separation optimized for speed.

Ultrahigh throughput is shown for ultrafast gradients with over 60 % reduction of total analysis time using alternating column regeneration. This was accomplished with parallel injection by the second needle installed in the Agilent 1290 Infinity II Multisampler, which has a dual-needle option for the analysis of food preservatives.

Ultrahigh throughput is shown for ultrafast gradients with over 60 % reduction of total analysis time using alternating column regeneration. This was accomplished with parallel injection by the second needle installed in the Agilent 1290 Infinity II Multisampler, which has a dual-needle option for the analysis of food preservatives.

The Agilent 1290 Infinity II High Dynamic Range Diode Array Detection Impurity Analyzer Solution combines the signals from two diode array detectors with different path length Max-Light cartridge cells to increase the linear dynamic UV-range. This solution can be used to detect and quantify main and trace compounds in a single run without exceeding the linear UV-range.

"This Application Note shows the analysis of 20 explosives with the Agilent 1290 Infinity II Variable Wavelength Detector (VWD) in dual-wavelength mode using 254 and 214 nm."

"This Application Note shows the analysis of 20 explosives with the Agilent 1290 Infinity II Variable Wavelength Detector (VWD) in dual-wavelength mode using 254 and 214 nm."

This application note demonstrates how comprehensive 2D-LC can be used to resolve the complex mixture of hydrophilic phenols found in virgin olive oil and investigates differences in the phenol composition of several olive oils.



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Published: January 11th 2016 | Updated:

Published: January 11th 2016 | Updated:

Published: January 11th 2016 | Updated: