Sonja Schneider

Articles

This application note demonstrates the analysis of charge variants of Rituximab (both innovator and biosimilar molecules) using multiple heart-cutting two-dimensional liquid chromatography (2D-LC) with mass spectrometry (MS) detection.

2D-LC –MS Characterization of Charge Variants Using Ion Exchange and Reversed-Phase Chromatography

2D-LC–MS Characterization of Charge Variants Using Ion Exchange and Reversed-Phase Chromatography

This Application Note demonstrate ultrafast gradients with an over 60 % reduction of analysis time using the Agilent 1290 Infinity II Multisampler with dual-needle function and alternating column regeneration.

Author | Sonja Schneider