The Column-02-20-2014

The Column

Incognito investigates if changing the carrier gas really requires a full method revalidation.

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The Column

Chris Reddy from the Woods Hole Oceanographic Institution (WHOI) spoke to Alasdair Matheson of The Column about the role of chromatography in the ongoing environmental analysis of the Deepwater Horizon oil spill, how GC×GC works in practice, and why this oil spill led to the return of thin layer chromatography (TLC) to his laboratory.

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The Column

The detection and quantitation of allergens in complex cosmetics extracts using two-dimensional gas chromatography–time-of-flight mass spectrometry (GC×GC–TOF-MS) is described. In particular, variable-energy electron ionization is shown to enhance both the sensitivity and selectivity of analyses by generating mass spectra containing structurally significant fragment ions with an improved molecular ion signal.

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The Column

Incognito investigates if changing the carrier gas really requires a full method revalidation.