The Column-06-05-2015

Tips & Tricks GPC/SEC: Answering Common Questions About GPC/SEC Columns

The Column

Using GPC/SEC for Excipient Characterization

Advances in Microsampling for In Vivo Pharmacokinetic Studies in Rodents

A look to the upcoming symposium on the Recent Developments in Pharmaceutical Analysis (RDPA 2015), which will be held 28 June to 1 July 2015 in Perugia, Italy.

A novel microdestructive capillary electrophoresis (CE) method for the analysis of blue pen ink strokes has been published. The analysis of pen inks can be challenging because ink compositions are usually under patent, the samples are small, and inks can degrade over time.

Fracking activity in the northeast of the USA has rapidly increased over recent years, with over 8000 Marcellus wells drilled in the Marcellus Formation in Pennsylvania, USA, alone. Scientists in Pennsylvania investigating an isolated contamination incident have published data from their study, demonstrating the application of comprehensive 2D gas chromatography coupled with time-of‑flight mass spectrometry (GC×GC–TOF-MS) to investigate fracking contamination in a drinking water source.

The Column

Parabens are commonly used in cosmetics and personal care products to protect against microbial growth, but a new study suggests that manufacturers may also be using parabens in plastic teething products designed for infants. Scientists applied an effect-directed approach (to determine endocrine disrupting ability) to analyze teething products prior to chemical analysis using gas chromatography coupled to mass spectrometry (GC–MS). Of 10 products were tested, two were found to contain endocrine disrupting chemicals (EDCs).

Click the title above to open The Column June 05, 2015 Europe & Asia issue, Volume 11, Number 10, in an interactive PDF format.

Click the title above to open The Column June 05, 2015 North American issue, Volume 11, Number 10, in an interactive PDF format.