Wolfgang Radke | Authors

The benefits of a molar mass distribution over molar mass averages and the differences between the different representations of molar mass distributions are discussed.

This instalment of Tips & Tricks focuses on whether a complete separation can be achieved using GPC/SEC and, if so, under what conditions.

Often incorrect conclusions on molar mass and molar mass distribution are drawn by simply looking at a chromatogram. However, certain valuable information can be obtained directly from the chromatogram. This instalment of Tips & Tricks will deal with some common misinterpretations of chromatograms.

This instalment describes the interplay between column length, pore size distribution, and particle size to optimize GPC/SEC separations.

Hydrolyzed collagens (collagen peptides) are water-soluble products obtained by hydrolysis of natural proteins and used for dietary supplements. A simple GPC/SEC method is described for molar mass determination of collagen peptides, allowing reliable molar mass determination using ultraviolet (UV) detection.

How to create a calibration curve when no chemically-matching reference materials with narrow molar mass distribution are available.