The Column-11-23-2016

The Column

Vol 12 No 21 The Column November 23, 2016 Europe and Asia PDF

November 23, 2016

Issue PDF

12

21

Click the title above to open The Column November 23, 2016 Europe & Asia issue, Volume 12, Number 21, in an interactive PDF format.

Vol 12 No 21 The Column November 23, 2016 North American PDF

November 23, 2016

Issue PDF

12

21

Click the title above to open The Column November 23, 2016 North American issue, Volume 12, Number 21, in an interactive PDF format.

Nasal Spray Evaluation Using Thin Layer Chromatography

November 17, 2016

News

12

21

Research on nasal spray formulation has yielded an improved in vitro analytical test method utilizing thin layer chromatography (TLC). The research used simulated nasal mucus with varying properties and a TLC apparatus to assess the dripping behaviour of nasal formulations to improve the nasal spray development process.Nasal Spray Evaluation Using Thin Layer Chromatography

Rudolf Krska Receives B.R.A.I.N Award

November 17, 2016

News

12

21

Rudolf Krska of the University of Natural Resources and Life Sciences (BOKU), in Vienna, Austria, has been awarded the biennial B.R.A.I.N award at the Biomin scientific conference held in Vancouver, Canada.

Phenomenex CEO Announces $12 Million in Bonuses Following Sale

November 17, 2016

News

12

21

Phenomenex’s CEO Fasha Mahjoor has announced $12 million in bonuses for the company’s staff following the sale of Phenomenex Inc. to Danaher Corporation in October 2016.

James Jorgenson Awarded Csaba Horváth Medal

November 17, 2016

News

12

21

Professor James Jorgenson of the University of North Carolina at Chapel Hill, in North Carolina, USA, has received the Csaba Horváth Medal and Scroll at the Csaba Horváth Memorial Award Symposium, Yale West Campus Conference Center.

Modernizing, Managing, and Complying with Regulatory Advances in Science

November 17, 2016

Features

12

21

Change, while scary, is a necessity. Opportunities for increased efficiency, higher profitability, and the ability for an organization to maintain a competitive advantage necessitate the need for change. Correctly adopting new liquid chromatography (LC) technology can be very challenging, however, when done correctly, modern LC technology can give a laboratory the ability to simplify method transfer across a diversity of analytical LC platforms at all of its facilities.

From HPLC to UHPLC — And Back

November 17, 2016

Features

12

21

Although ultrahigh-pressure liquid chromatography (UHPLC) method development is fast and cost efficient, many of the analytical methods used in quality control laboratories are still conventional high performance LC (HPLC) separations. Transferring these HPLC methods to UHPLC and validating them is a time-consuming and labour-intensive task. Nevertheless, switching methods from HPLC to UHPLC equipment and vice versa is a powerful tool to increase laboratory efficiency. Modern systems with two flow lines in one system aim to simplify the transition between the two techniques.

What’s New in the Analysis of Complex Environmental Matrices?

November 17, 2016

Features

12

21

The Royal Society of Chemistry’s Environmental Chemistry Group, Water Science Forum, and the Separation Science Group Joint Meeting will be held on Friday 3 March 2017 at the Science Suite of the Royal Society of Chemistry, in Burlington House, Piccadilly, London, UK.

UHP-SEC-MALS: Enhanced Biophysical Characterization of Biotherapeutics with Light Scattering and UHPLC

November 17, 2016

Cover Story

12

21

Faster analyses, better separations, and lower consumption of sample and mobile phase are the primary drivers of size-exclusion chromatography with sub-2-µm beads and ultrahigh-pressures (UHP-SEC). The flip side of these benefits is higher sensitivity to column calibration errors and drift. There is also a relatively small selection of column chemistries available for eliminating non-ideal sample-column interactions. UHP-SEC can be combined with on-line multi-angle light scattering (UHP-SEC-MALS) to overcome these limitations and provide absolute molar mass and size of biomacromolecules, independently of retention time. UHP-SEC-MALS is also necessary for UHP-SEC characterization of proteins and biotherapeutics that have no appropriate reference standards, such as glycoproteins and PEGylated proteins.