LCGC Europe-04-01-2016

LCGC Europe

Magnetic nanoparticles (m-NPs) are becoming important in analytical chemistry as sorbents in dispersive solid-phase extraction (d-SPE) because they simplify the extraction process and save time as a result of their isolation from the sample matrix by an external magnetic field. Many synthetic processes have been developed to fabricate these nanomaterials and an additional coating step is usually included at the end of the synthesis to improve their stability and to avoid the formation of agglomerates. A wide variety of coatings have been used for this purpose to improve selectivity. This manuscript provides an overview of the different synthesis methods, coatings, and applications of m-NPs as sorbents in d-SPE.

Recent progress in supercritical fluid chromatography (SFC) instrumentation has led to renewed interest in the technique as a powerful tool for chiral and achiral separations of pharmaceutical molecules, for both analytical and preparative purposes. The “green” aspect of the technique and low running costs make SFC technology particularly attractive for preparative chromatography because it considerably reduces the consumption of organic solvents. These factors led to a revised strategy for purification and to a general interest in evaluating possible extensions for the application of packed SFC (pSFC). The results of this extensive evaluation have led to the establishment of SFC platforms for preparative achiral purifications as a standard practice, alongside its use for preparative chiral separations.

Columns
LCGC Europe

April 21, 2016

What should you do if your retention times drop from one injection to the next? A systematic approach to troubleshooting can help to quickly identify the problem source.

The 40th International Symposium in Capillary Chromatography (ISCC) and 13th GC×GC Symposium will be held at the Palazzo dei Congressi, in Riva del Garda, Italy, from 29 May–3 June 2016.

Our annual review of new liquid chromatography (LC) columns and accessories introduced at Pittcon and throughout the previous year.

Click the title above to open the LCGC Europe April 2016 Analytica Guide Supplement, Vol 29, No s4, in an interactive PDF format.

Click the title above to open the LCGC Europe April 2016 Chromatography and Sample Preparation Terminology Guide Supplement, Vol 29, No s4, in an interactive PDF format.

Issue PDF
LCGC Europe

April 01, 2016

Click the title above to open the LCGC Europe April 2016 regular issue, Vol 29, No 4, in an interactive PDF format.