LCGC Europe-08-01-2012

An excerpt from LCGC's e-learning tutorial on HPLC for reversed-phase separations at Chromacademy.com.

A pioneer in high performance liquid chromatography reflects on his career and how "enlightened trial-and-error" can reduce the effort involved in method development.

This article describes the GC–MS and LC–MS screening methods developed by the Environment Agency for England and Wales for the analysis of both low-volumn water samples and extracts obtained from various designs of passive samplers.

This article provides examples of the use of SLE, demonstrates some of its advantages and provides commercial sources for SLE products.

Retention-time drift, temperature control and broad peaks from a new column are the topics of this month's discussion.

Event news

The statistical nature of experiments leads to the fact that standard deviation (SD) of replicate analysis is not constant but a number with some variability: a standard deviation has its own standard deviation. As a consequence, a SD calculated from three experiments is not rugged and even SDs from ten experiments show a great variability. Analysts should be aware that with 100 or more the results have low scatter