LCGC Europe-09-01-2020

This article will review historical bonding techniques still in use for manufacturing high performance liquid chromatography (HPLC) stationary phases today, and also examine some emerging technologies that may be able to tackle unmet needs in novel platforms and phase construction.

In this study, a method was developed for extraction and preconcentration of trace amounts of organophosphorus pesticides (OPPs), including fenitrothion, chlorpyrifos-methyl, and chlorpyrifos in environmental water.

Gas chromatographs today are easy to use. With modern web-based controls and data analysis, you don’t even have to be in the laboratory to run the instrument and collect the data. In this first instalment on how this magic happens, we discuss signal generation and processing from a classical flame ionization detector (FID), so that you can use the data to make decisions.

A handful of approximate rules about the behaviour of reversed-phase liquid chromatography (LC) can facilitate more efficient work, both during method development and in troubleshooting problems that arise with LC systems.

This article uses case studies to explore the use and misuse of spreadsheet calculations in conjunction with a chromatography datasystem (CDS) in regulated GXP laboratories. What wonders of non-compliance will we find? How and when should spreadsheets be used in chromatographic analysis?