Special Issues
April 03, 2013
Issue PDF
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Click the title above to open the LCGC North America April 2013 Recent Developments in HPLC and UHPLC Supplement, Vol 31 No s4, in an interactive PDF format.
April 02, 2013
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A summary of the latest in new ion-exchange phases for ion chromatography, with a focus on general aspects of phase design and then a review of anion-exchange and cation-exchange columns introduced in the past few years
April 02, 2013
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A look at the current status of detection in ion chromatography, focusing on the most popular detectors in IC: the conductivity detector and the charge detector
April 02, 2013
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From the invention of eluent suppression to today's "just add water" concept, pivotal developments over the last 40 years are chronologically highlighted from a chemical and instrumental viewpoint.
April 02, 2013
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The speed of IC has been limited by pressure and flow limits of the hardware. Recent advances are enabling faster IC separations.
April 01, 2013
Articles
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The parameters that should be considered in the optimization of HPLC methods are explained and then illustrated through the analysis of two commercial agricultural products.
April 01, 2013
Articles
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A new type of method development that uses modeling to find the "best" separation for high performance liquid chromatography (HPLC) was investigated and principles of Quality by Design (QbD) were followed when planning the investigation. The process delivered precise results and the method was able be transferred to a routine quality control (QC) laboratory.
April 01, 2013
Articles
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A demonstration of how to successfully convert from capillary zone electrophoresis to dual-opposite injection capillary zone electrophoresis for routine experiments is outlined.
April 01, 2013
Articles
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Supercritical fluid chromatography has become a viable option for the separation scientist in diverse areas, and the field now seems more adequately described as an extension of HPLC, or perhaps as "carbon dioxide–based HPLC."
April 01, 2013
Introduction
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When choosing the articles to include in this supplement, my selection was based on a very simple criterion. My invitations went to the researchers that typically have something to say that I am interested in learning.
April 01, 2013
Articles
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The authors explain modern UHPLC instrument design and outline simple procedures to identify causes of poor column and method performance.
April 01, 2013
Articles
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This article discusses useful approaches for the resolution of overlapping and superimposed peaks in HPLC.