Advancements in Semi-Volatiles Analysis for EPA 8270 Using GC–MS Single- and Triple-Quadrupole Techniques - August



Webinar Date/Time: Wed, Aug 23, 2023 11:00 AM EDT

Learn about the latest advancements in Agilent GC–MS instrumentation and techniques, such as increased sensitivity, Retention Time Locking, and Multiple Reaction Monitoring (MRM), which offer significant advantages for analyzing semi-volatile organic compounds (SVOCs) in solid wastes, soils, and water samples according to the United States Environmental Protection Agency (US EPA) Method 8270. Join our webcast to discover how these innovations can enhance sustainability, reduce costs, and provide faster, more confident results in your laboratory.

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Event Overview:

United States Environmental Protection Agency (US EPA) Method 8270 provides regulation and guidance for the analysis of semi-volatile organic compounds (SVOCs) by gas chromatography–mass spectrometry (GC–MS) in solid wastes, soils, and water samples. Many advancements have been made in Agilent GC–MS instrumentation and techniques that offer significant advantages.

  • Increased sensitivity can facilitate smaller extraction volumes that increase sustainability, reduce waste, and decrease costs associated with sample preparation, solvent usage, and waste disposal.
  • Retention Time Locking can protect against losing peaks that may otherwise drift out of an analysis window after column trimming.
  • Method 8270E provides guidance for analysis with GC/TQ instrumentation. Multiple Reaction Monitoring (MRM) from a GC/TQ results in faster batch review and increased confidence due to the elimination of matrix interferences that are often present when using SIM or Scan acquisition modes. This also provides the ability to simultaneously increase the number of analytes and speed up the analysis which can result in significantly increased capacity and time savings.
  • The guidance of a Manufacturer’s Recommended Tune protocol assists the analyst to quickly evaluate the operability of the analytical instrument.

This webinar will discuss these as well as other advancements in GC/SQ and GC/TQ hardware and analytical techniques that can improve results in the laboratory.

Key Learning Objectives:

  • Overview of Agilent’s manufacturer’s recommended tune protocol.
  • Comparison of advantages between Single-Quadrupole and Triple-Quadrupole for semi-volatiles analysis
  • Considerations for moving methods from SQ to TQ and vice versa
  • Key techniques for improving performance for high sensitivity semi-volatiles analysis.

Who Should Attend: 

  • Environmental lab managers or lab technicians
  • Scientists working with GC–MS/MS


Bruce Quimby
Senior GC/MS Applications Scientist
Agilent Technologies

Bruce Quimby, Ph.D. is a Senior Applications Scientist in the Mass Spectrometry Division of Agilent Technologies, located in Wilmington, Delaware. He is currently working on GC/MS applications in multiple areas including environmental and food safety.

Eric Fausett
Application Scientist
Agilent Technologies

Eric Fausett is an Application Scientist in the GC/MS division of Agilent Technologies. He works with new product introduction and method development on GC and GC/MS platforms.
Prior to his 8 years at Agilent, Eric worked for 15 years as a contractor to various US Government laboratories as a Project Scientist, GC Applications Chemist, and Laboratory Manager.

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