News|Articles|January 14, 2025
Analysis of Oligonucleotides Using an Ion-Pairing-Free Reversed-Phase Method with TOF LC/MS
Author(s)Agilent Technologies, Inc.
This app note describes a non ion-pairing reversed-phase LC/MS method for highly modified ASOs, DNA, sgRNA, and siRNA ranging from 14- to 103-mer oligonucleotides.
Newsletter
Join the global community of analytical scientists who trust LCGC for insights on the latest techniques, trends, and expert solutions in chromatography.
Related Content
Trending on LCGC International
1
Thermo Fisher and NVIDIA Partner to Expand AI Driven Laboratory Automation
2
Waters Corporation Shareholders Approve Share Issuance for Planned Combination with BD Biosciences and Diagnostics
3
QuEChERS–GC–MS/MS Chromatographic Method for Organochlorine Pesticide Residue Analysis in Sesame Seeds
4
Layer-Resolved Corneal Proteomics Enabled by Laser Ablation Sampling and LC–MS/MS
5