ASMS 2023: A Look at the Monday Morning Oral Session on Small Molecules

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From 8:30–10:30 am, there was another oral session titled, “Small Molecules: Structural Characterization and Quantitation,” which took place in Ballroom C. The session, chaired by Athula Attygalle of Stevens Institute of Technology, featured six talks about the different techniques and methods that have been used for the structural characterization and quantitation of small molecules.

At 8:30 am, Takemichi Nakamura from RIKEN in Wako, Japan, kicked off the session by reflecting on a few natural product cases when conducting structural analysis of organic compounds based on spectral appearance.

Next, at 8:50 am, Bela Paizs of Rosalind Franklin Institute, in Didcot, United Kingdom, and of Deshape in London, United Kingdom, discussed using modelling and an advanced fragmentation model when characterizing the structure of small molecules.

John M. Eiler of the California Institute of Technology was the third speaker in this oral session. At 9:10 am, he delivered a talk about the present and future of high-precision isotope measurements in life science studies.


Then, at 9:30 am, Atena Tajaddodi of Wichita State University delivered a talk about the isomeric characterization of illicit drugs using high-resolution linear and differential ion mobility separations.

Following the 9:30 talk was the fifth talk of the session, which was delivered by Ming Yao of Bristol-Myers Squibb at 9:50 am. Yao’s talk focused on the structural elucidation of conjugation drug metabolites by utilizing novel electron-activated dissociation (EAD).

To conclude this session, at 10:10 am, Fangling Wu of Ningbo University in Ningbo, China, talked about the analysis of thyroxine enantiomers in pharmaceuticals by ion mobility analysis based on molecular complexes.