Brian Bidlingmeyer, long-time LCGC Editorial Advisory Board member, received the 2010 Eastern Analytical Symposium (EAS) Award for Outstanding Achievements in Separation Science on Tuesday, November 16, 2010.
Brian Bidlingmeyer, long-time LCGC Editorial Advisory Board member, received the 2010 Eastern Analytical Symposium (EAS) Award for Outstanding Achievements in Separation Science on Tuesday, November 16, 2010. The award was sponsored by Agilent Technologies. Past winners of the award include distinguished chromatographers such as Peter Schoenmakers, Pat Sandra, Phyllis Brown, Peter Carr, Lloyd Snyder, Jack Kirkland, Dan Armstrong, Harold McNair, and Csaba Horvath.
Bidlingmeyer studied for his undergraduate degree at Kenyon College in Gambier, Ohio. He received his Ph.D. degree in Analytical Chemistry while studying under Prof. L.B. Rogers at Purdue University in West Lafayette, Indiana. His thesis at Purdue described the use of liquid chromatography at pressures ranging from 10,000 to 60,000 psi. Bidlingmeyer then worked at Amoco Research Center in Naperville, Illinois, where he developed key separation-based methods for ensuring product quality. Following his employment at Amoco, he began working at Waters Associates as an application chemist. His work at Waters involved application-focused products. He eventually became Vice-President and Technical Director for Waters Chromatography Division of Millipore Corporation. Bidlingmeyer left Waters to cofound Cohesive Technologies, where in partnership with the 3M Company he introduced a column based on a porous zirconia substrate. He then joined Sterling Winthrop Pharmaceuticals as an Assistant Director with a focus on separation sciences. He left that company to join Rockland Technologies in Wilmington, Delaware, which was purchased by Hewlett Packard in 1997. Agilent Technologies was created from part of Hewlett Packard in 1999, and Bidlngmeyer continued his work with the company’s separation products business unit. Currently he is a senior R&D scientist in the company’s Columns and Supplies Division.
Bidlingmeyer has worked with and promoted high performance liquid chromatography (HPLC) for most of his career. He has developed and presents several short courses for groups such as the American Chemical Society (ACS). He is the Chairman of the Separations Science and Separations Chemistry Subdivision of ACS’s Analytical Division. His current areas of research include separation mechanisms, problem solving in challenging applications, and developing new and improved commercial products.
GC–TOF-MS Finds 250 Volatile Compounds in E-Cigarette Liquids
November 1st 2024A study has used gas chromatography coupled to a time-of-flight mass spectrometer to build an electron ionization mass spectra database of more than 250 chemicals classified as either volatile or semi-volatile compounds. An additional, confirmatory layer of liquid chromatography–mass spectrometry analysis was subsequently performed.
AI and GenAI Applications to Help Optimize Purification and Yield of Antibodies From Plasma
October 31st 2024Deriving antibodies from plasma products involves several steps, typically starting from the collection of plasma and ending with the purification of the desired antibodies. These are: plasma collection; plasma pooling; fractionation; antibody purification; concentration and formulation; quality control; and packaging and storage. This process results in a purified antibody product that can be used for therapeutic purposes, diagnostic tests, or research. Each step is critical to ensure the safety, efficacy, and quality of the final product. Applications of AI/GenAI in many of these steps can significantly help in the optimization of purification and yield of the desired antibodies. Some specific use-cases are: selecting and optimizing plasma units for optimized plasma pooling; GenAI solution for enterprise search on internal knowledge portal; analysing and optimizing production batch profitability, inventory, yields; monitoring production batch key performance indicators for outlier identification; monitoring production equipment to predict maintenance events; and reducing quality control laboratory testing turnaround time.
Multivariate Design of Experiments for Gas Chromatographic Analysis
November 1st 2024Recent advances in green chemistry have made multivariate experimental design popular in sample preparation development. This approach helps reduce the number of measurements and data for evaluation and can be useful for method development in gas chromatography.