Brandon Ruotolo Wins the 2023 Biemann Medal
Brandon Ruotolo, University of Michigan
Brandon Ruotolo, a professor of chemistry at the University of Michigan, has been named the 2023 recipient of the ASMS Biemann Medal. He will receive the medal at the 2023 ASMS Conference in Houston, Texas, which takes place June 4–8.
The Biemann Medal recognizes significant achievements in basic or applied mass spectrometry in the early stages of an academic career. In addition to the medal, each recipient is invited to speak as part of an award lecture and given a $5000 cash award.
Ruotolo has made significant contributions to the development and application of novel high performance mass spectrometry (MS) technologies for the broader part of his career, with a focus on applications of high impact to the biology and medical communities. Examples of his career achievements include leadership in the development of ion mobility MS (IM-MS) for structural characterization of biopolymers; refinement of collision induced unfolding (CIU) methods that enable determination of the number of autonomously folded domains within proteins and characterization of stability reflective of changes in both local and global protein structure; the use of CIU to prob the relative stability of protein-ligand interactions; the development of chemical cross-linkers to stabilize protein structure in the absence of bulk solvent; integration of IM-MS and other structural MS methods as a high-throughput approach for structural proteomics; and the application of IM-MS as a screening tool for therapeutic drug discovery.
TD-GC–MS and IDMS Sample Prep for CRM to Quantify Decabromodiphenyl Ether in Polystyrene Matrix
April 26th 2024At issue in this study was the certified value of decabromodiphenyl ether (BDE 209) in a polystyrene matrix CRM relative to its regulated value in the EU Restriction of Hazardous Substances Directive.
LC–MS/MS-Based System Used to Profile Ceramide Reactions to Diseases
April 26th 2024Scientists from the University of Córdoba in Córdoba, Spain recently used liquid chromatography–tandem mass spectrometry (LC–MS/MS) to comprehensively profile human ceramides to determine their reactions to diseases.
High-Throughput 4D TIMS Method Accelerates Lipidomics Analysis
April 25th 2024Ultrahigh-pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) had been previously proposed for untargeted lipidomics analysis, but this updated approach was reported by the authors to reduce run time to 4 min.
