In this article, Jo Webber tackles the problem of ensuring data integrity in pharmaceutical manufacturing. She shows how, by using modern technology and well integrated systems, quality can be improved.
In-Loop Analyte Degradation in Two-Dimensional Liquid Chromatography: Example and Solutions
September 13th 2024In this installment of “LC Troubleshooting,” we describe an artifact that can arise because of compound degradation during the transfer of fractions of the first dimension (1D) column effluent to the 2D separation.