Adjusting Conditions for a Routine Reversed-Phase HPLC Assay, Part 1: Changing the Column

April 1, 2005
Lloyd R. Snyder

John W. Dolan
John W. Dolan

John Dolan has been writing "LC Troubleshooting" for LCGC for over 20 years. One of the industry's most respected professionals, John is currently the Vice President of BASi Northwest Laboratory, McMinnville, Oregon and a principal instructor for LC Resources, Walnut Creek, California. He is also a member of LCGC's editorial advisory board.

LCGC Europe

LCGC Europe, LCGC Europe-04-01-2005, Volume 18, Issue 4
Pages: 196–203

Columns | <b>Column: Column Watch</b>

In the first part of this series, the authors look at method modification from a scientific and regulatory standpoint with regard to changing a column and the operating parameters.