This application news presents instrument operating conditions and
instrument method performance statistics, including method linearity, accuracy, and precision,
for priority pollutant pesticides and PCB congeners. The method validated in this application acted
as guidance in developing ASTM D8543 Test Method for Determination of OCPs and PCBs in
Aqueous Solution by a GC/MS/MS which is intended for proposal to EPA as an alternative test
procedure (ATP) for EPA 608.3
In this fifth part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor discusses how to overcome challenges with reversed-phase chromatography in drug analysis.
This week on Chromatography Online, leading experts shared practical insights with LCGC International on sustainable affinity methods, siRNA impurity profiling, nontarget screening, peptide tech transfer, and AI in separation science.
Anneli Kruve reports that toxicity predictions from MS2-derived molecular fingerprints outperform spectral-similarity methods in nontarget screening of food.
In this fourth part of " Conversations with Michael Dong," a series on fundamentals of HPLC in pharmaceutical analysis, LCGC International’s "Perspectives in HPLC" column editor explains why buffers are most often used in Mobile Phase A in high-pressure liquid chromatography of pharmaceuticals.