This application news presents instrument operating conditions and
instrument method performance statistics, including method linearity, accuracy, and precision,
for priority pollutant pesticides and PCB congeners. The method validated in this application acted
as guidance in developing ASTM D8543 Test Method for Determination of OCPs and PCBs in
Aqueous Solution by a GC/MS/MS which is intended for proposal to EPA as an alternative test
procedure (ATP) for EPA 608.3
How feasible is it to integrate this Bayesian graph-theory methodology into existing commercial chromatography software workflows for semi-automated data curation in routine analytical laboratories?
Gabriel Vivó-Truyols outlines the benefits and challenges of combining graph theory with Bayesian statistics to automate peak assignment and alignment.
This week, Chromatography Online’s coverage spanned lipidomics-based early cancer detection, career paths in separation science, machine learning and uncertainty-driven approaches to LC method development, new EU wastewater rules for pharmaceutical micropollutants, automated Separation Quality Factor (SQF) evaluation in chromatography data systems, and solutions to GLP-1 peptide analysis challenges.
Gabriel Vivó-Truyols from the Spanish Council for Scientific Research, Madrid, Spain. discusses his work on using graph theory and Bayesian statistics for peak assignment and chromatographic alignment.
Gas chromatography–mass spectrometry (GC–MS) and liquid chromatography-quadrupole time-of-flight mass spectrometry (LC–qTOF–MS) reveal metabolic shifts in tricuspid regurgitation.