Exploring the Application of MALDI-IHC with Bottom-up Proteomics: An ASMS Interview with Ron Heeren
At ASMS 2023, LCGC spoke with Ron Heeren of Maastricht University. This segment previews one of several ASMS interviews that were conducted at the conference.
Heeren spoke with us at ASMS 2023 in Houston, Texas, where he briefed us on his current research endeavors that involve using multiplexed matrix-assisted laser desorption/ionization–immunohistochemistry (MALDI-IHC) with image-guided proteomics to further investigate diseases. The idea is that MALDI-IHC with image-guided proteomics can provide information from the same tissue section without the need for customized and complex instrumentation.
Heeren is a Distinguished Professor and and Limburg co-chair of the Maastricht Multimodal Molecular Imaging Institute in the Division of Imaging Mass Spectrometry at Maastricht University.
In this video interview, Heeren answers the following questions:
- How does MALDI-IHC combine MALDI mass spectrometry imaging and immunohistochemistry for targeted tissue imaging?
- What advantages does MALDI-IHC offer over traditional IHC in studying specific biomolecules in tissues?
- What insights can be gained from integrating MALDI-IHC with bottom-up proteomics in breast cancer research?
- How can MALDI-IHC and image-guided proteomics contribute to disease understanding and the development of new approaches?
- What are the next steps in a future study on this subject?
Our interview with Heeren was one of several conducted live at ASMS 2023. Stay tuned for our other interviews conducted at ASMS.
Pittcon 2025: Regenerative Engineering Takes Center Stage at Keynote Coulter Lecture
March 3rd 2025Cato T. Laurencin, MD, PhD, who is well-known as a scientist and entrepreneur with an extensive career in regenerative engineering, delivered the Wallace H. Coulter lecture yesterday. Here are some of the highlights from the talk.
LCGC Pittcon Session Highlights Christopher Pohl, Katelynn Perrault Uptmor, and More Top Experts
February 28th 2025Each year, LCGC International presents two awards at Pittcon to the winner of the Lifetime Achievement in Chromatography Award and the Emerging Leader in Chromatography Award. This year, Christopher Pohl is the recipient of the Lifetime Achievement Award and Katelynn Perrault Uptmor is the recipient of the Emerging Leader award. The award presentation, which will honor Pohl and Perrault Uptmor, will take place on Tuesday March 4th from 8:30–11:40 am.
