Fluorinated Monolithic Columns for LC
Researchers from Queen's University (Kingston, Ontario, Canada) developed porous polymer capillary columns with varied flurous content for chromatography of tagged analytes.
Researchers from Queen's University (Kingston, Ontario, Canada) developed porous polymer capillary columns with varied flurous content for chromatography of tagged analytes. They used a UV-initiated radical polymerization process to create the monolithic columns and tested them using flow-induced back pressure and scanning electron microscopy. The columns were able to separate fluorous-tagged analytes under gradient conditions, and the researchers found that the fluorinated monolithic columns exhibited greater selectivity for fluorous analytes than did comparable nonfluorinated monolithic columns.
LC–MS/MS-Based System Used to Profile Ceramide Reactions to Diseases
April 26th 2024Scientists from the University of Córdoba in Córdoba, Spain recently used liquid chromatography–tandem mass spectrometry (LC–MS/MS) to comprehensively profile human ceramides to determine their reactions to diseases.
High-Throughput 4D TIMS Method Accelerates Lipidomics Analysis
April 25th 2024Ultrahigh-pressure liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) had been previously proposed for untargeted lipidomics analysis, but this updated approach was reported by the authors to reduce run time to 4 min.
Traditional Chinese Medicine’s Effects on Liver Cancer Measured Using New UHPLC–QTOF-MS System
April 22nd 2024Scientists from Anhui University of Chinese Medicine in Hefei, China recently investigated the mechanisms behind what makes huachansu tablets, a type of traditional Chinese medicine (TCM), effective against liver cancer.
