News|Articles|May 4, 2026

From Contamination to Compliance: The Role of Sartorius' Lab Water System in PFAS Detection (May 2026)

Author(s)Sartorius

PFAS are persistent “forever chemicals” used across multiple industries and found in the environment. This application note explores LC-MS/MS and CIC methods showing how Arium® Comfort I UV reduces PFAS contamination in water to ultra-trace levels, enabling reliable detection, improved sustainability, and cost-effective in-house ultrapure water production.


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Figure 2. Split injection used to measure triplicate test of MTBE, hexane, o-xylene, and 1-methylnaphthalene comparing different solvents (methanol, methylene chloride) and column insertion distances starting with 0.5 mm, 5.0 mm, 10.0 mm, 15 mm, and 20.0 mm. Methanol had the best performance at the 5.0 mm insertion distance and methylene chloride looked slightly better at the 0.5 mm. We would still recommend not going below the 5.0 mm manufacturer recommended insertion distance.
Revisiting insertion distance for methanol and methylene chloride in GC analysis and confirming that insertion depth strongly affects response and reproducibility.
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