Generic Method for the Extraction of Basic Drugs from Biological Fluids Using ISOLUTE® Mixed-Mode SPE Columns and 96-Well SPE Plates

Article

LCGC North America

LCGC North AmericaLCGC North America-06-02-2002

Solid-phase extraction of basic drugs. (Argonaut Technologies)

External Link - article-23475.pdf

Articles in this issue
Simplified Method Development for the Extraction of Acidic, Basic, and Neutral Compounds with a Single SPE Sorbent — Strata X™
New High Performance Amylose Chiral Columns: CHIRALPAK AS-H and CHIRALPAK AS-RH
Polymer Characterization Using Liquid Chromatography with Evaporative Light-Scattering Detection
Generic Method for the Extraction of Basic Drugs from Biological Fluids Using ISOLUTE® Mixed-Mode SPE Columns and 96-Well SPE Plates
Fast and Easy Physiological Amino Acids Analysis in 15 Min
Industrial Solvents Analyzed on SolGel-WAX™
Gelatins
Using Polar Stationary Phases to Retain 3',5'-Cyclic Nucleotides in RPLC
Efficient HPLC Separation of Herbicide Enantiomers on the New DACH-DNB Chiral Stationary Phase
Fast Methods for Structurally Similar Compounds Using Carbon HPLC Columns
Retention-Time Locking: Advantages in GC–MS SIM Acquisitions
Identification of Polymer Additives Using a Combination of GC–MS and LC–MS
LC–MS–MS Analysis of Terfenadine and Its Metabolites in Rat Plasma Using Oasis® MCX
Quantitation and Profiling of Orange Juices and Orange Drinks Using Fast HPLC and Evaporative Light-Scattering Detection
Exceptional Selectivity and Resolving Power of 300-Å Pore for Proteins and 90-Å for Peptides Mapping
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Angela I. Calderón is a Gilliland Endowed Professor in the Department of Drug Discovery and Development, Harrison College of Pharmacy, Auburn University. She received her B.S. in Pharmacy from the University of Panama, Panama City, Republic of Panama (1990), MSc. in Pharmacognosy from the University of Illinois at Chicago, Chicago, Illinois under the supervision of Dr. Djaja Djendoel Soejarto and Dr. Cindy K. Angerhofer (1997), and Ph.D. in Pharmacognosy from the University of Lausanne, Lausanne, Switzerland under the guidance of Prof. Kurt Hostettmann (2002). Then, she conducted her postdoctorate on biomedical applications of mass spectrometry at Prof. Richard B. van Breemen’s laboratory at the University of Illinois at Chicago (2006-2008). She joined the faculty at Auburn University College of Pharmacy as an Assistant Professor in August 2008. Dr. Calderón specializes in natural drug products research, specifically applications of mass spectrometry to natural products drug discovery, and quality and safety assessment of botanical dietary supplements. Over the last sixteen years, she has authored 52 publications, 1 US patent, and 5 book chapters. She also has received research funding from agencies that include National Center for Complementary and Integrative Health (NCCIH) and the Office of Dietary Supplements (ODS) of the National Institutes of Health (NIH), American Society of Pharmacognosy, United States Pharmacopeia, Auburn University Research Initiative in Cancer (AURIC), and botanical dietary supplements industry. Dr. Calderón is currently an expert member of the United States Pharmacopeia Botanical Pan-American Expert Panel. She also was a member of the United States Pharmacopeia Botanical Dietary Supplements and Herbal Medicines Expert Committee. Additionally, she was the Section Editor of Pharmacognosy of Combinatorial Chemistry & High Throughput Screening and Pharmaceutical Biology and is a current member of the Advisory Board of Planta Medica She has been grant proposal reviewer for National Institutes of Health (NIH), National Science Foundation (NSF), USA and German Federal Ministry of Education and Research (BMBF) and Project Management Jülich (PtJ) and Deutsche Forschungsgemeinschaft (German Research Foundation), Germany, and International Foundation for Science (IFS), Sweeden.

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