News|Articles|February 9, 2024
High-Sensitivity Oligonucleotide Analysis Using Ion-Pairing-Free HILIC and TOF LC/MS
Author(s)Agilent Technologies, Inc.
This application note presents an alternative method using time-of-flight liquid chromatography/mass spectrometry (TOF LC/MS) and hydrophilic interaction chromatography (HILIC) that enables accurate and repeatable analysis of diverse oligonucleotides without using ion-pairing reagents.
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