Liquid-Liquid-Liquid Microextraction of Nerve Agents

Researchers from Vertox Laboratory, Defence Research and Development Establishment (Gwalior, India) used a liquid-liquid-liquid microextraction technique followed by liquid chromatography?mass spectrometry (LC?MS) to examine alkyl alkylphosphonic acids, which are important environmental markers of nerve agents.

Researchers from Vertox Laboratory, Defence Research and Development Establishment (Gwalior, India) used a liquid-liquid-liquid microextraction technique followed by liquid chromatography–mass spectrometry (LC–MS) to examine alkyl alkylphosphonic acids, which are important environmental markers of nerve agents. In their technique, the acids were extracted froman acidified aqueous phase to an organic phase located in the pores of a hollow fiber. They were then back extracted into an alkaline acceptor phase in the lumen of the fiber. The researchers validated the method and then applied it to detection of the acids in a water sample provided by the Organization for Prohibition of Chemical Weapons during a proficiency test.