HPLC column stability is a critical factor. This note describes how the Agilent Poroshell HPH-C18 column performed brilliantly in an elevated pH mobile phases such as ammonium bicarbonate buffer.
Analyze Charge Variants in Antibody-Based Therapeutics Using Cation Exchange Chromatography
July 18th 2024This application note discusses the latest development on high performance cation exchange bio-separation columns for determining charge variants in protein-based biotherapeutics, as well as the strategy on method development.