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© 2022 MJH Life Sciences and Chromatography Online. All rights reserved.
© 2022 MJH Life Sciences™ and Chromatography Online. All rights reserved.
HPLC column stability is a critical factor. This note describes how the Agilent Poroshell HPH-C18 column performed brilliantly in an elevated pH mobile phases such as ammonium bicarbonate buffer.
A novel approach to enhancing the selectivity of ionizable compounds using superficially porous particles that are stable in a wider pH range is reported here.
The most significant recent advancement in liquid chromatography (LC) column technology is the new generation of superficially porous silica particles.