A researcher from the National University of Kaohsiung (Kaohsiung, Taiwan) used micellar electrokinetic chromatography (MEKC) to preconcentrate and separate gold nanoparticles.
A researcher from the National University of Kaohsiung (Kaohsiung, Taiwan) used micellar electrokinetic chromatography (MEKC) to preconcentrate and separate gold nanoparticles. A reversed electrode polarity stacking mode approach was used for the on-line enhancement and separation. Parameters affecting the separation included the sodium dodecyl sulfate surfactant concentration, salts in the nanoparticle solution, the running electrolyte pH, and the capillary temperature. The researcher obtained enhanced detection sensitivities for the gold nanoparticles compared with those obtained using standard MEKC analysis conditions.
Transferring Methods to Compact and Portable HPLC
February 14th 2024The current trend in laboratory equipment design is the miniaturization of laboratory instruments. Smaller-scale HPLC instruments offer benefits that cannot be matched by analytical-scale equipment, especially in the areas of portability, reduced fluid volumes, and reduced operating costs. Yet, the miniaturization of laboratory equipment has brought with it a unique set of challenges, including transferring methods to compact LC. Capillary LC expands the use of LC to applications not currently done using conventional LC in a wide array of application areas, including pharmaceutical, food and beverage, petrochemical, environmental, and oil and gas. Greg Ward, Axcend’s CEO wrote, “Customers want an HPLC system with a small footprint, low flow rates and green chemistry.” Join his podcast where he shares method transfer in these application areas.