Mixed-Mode Cleanup Technique for Drug in Meat Products
Researchers from the Technical University of Denmark and (Lyngby, Denmark) and the Danish Meat Research Institute (Roskilde, Denmark) used a mixed-mode reversed phase?anion exchange cleanup method followed by LC-MS with electrospray ionization time-of-flight detection to analyze mycophenolic acid in dry-cured ham, fermented sausage, and liver pate.
Researchers from the Technical University of Denmark and (Lyngby, Denmark) and the Danish Meat Research Institute (Roskilde, Denmark) used a mixed-mode reversed phase–anion exchange cleanup method followed by LC-MS with electrospray ionization time-of-flight detection to analyze mycophenolic acid in dry-cured ham, fermented sausage, and liver pate. The mycophenolic acid, a compound used an immunosuppressant in organ transplantation, was first extracted from the meat with a bicarbonate–acetonitrile solution.
HPLC 2025 Preview: Functionalized Monoliths as Selective Sample Preparation Materials
May 16th 2025Analyzing trace compounds from complex samples often requires purification and pre-concentration, and online coupling of solid-phase extraction (SPE) with liquid chromatography (LC) helps minimize analysis time and solvent/sample use. Monoliths with large macropores are ideal for this coupling due to their low back pressure and versatility in various formats.
Thermodynamic Insights into Organic Solvent Extraction for Chemical Analysis of Medical Devices
April 16th 2025A new study, published by a researcher from Chemical Characterization Solutions in Minnesota, explored a new approach for sample preparation for the chemical characterization of medical devices.
