More Sensitive Quantification of PFAS by LC/MS with the Agilent 1260 Infinity II Hybrid Multisampler
This application note demonstrates the use of the Agilent 1260 Infinity II Hybrid Multisampler for the analysis of per- and polyfluorinated alkyl substances (PFAS). The Hybrid Multisampler in feed injection mode was used with optimized Feed Speed for the sample injection to trap and enrich the compounds on the column. This avoided peak broadening and breakthrough of the early-eluting polar PFAS compounds. The less polar PFAS compounds can be enriched for more sensitive quantification.
Analysis of Ultrashort-Chain and Short-Chain (C1 to C4) PFAS in Water Samples (May 2025)
May 15th 2025In this study, an accurate, reliable analytical LC-MS/MS method for PFAS in water was developed to specifically quantify C1 to C4 PFAS in both potable and non-potable sources. A direct injection workflow was implemented to simplify the testing process and to avoid potential contamination originating from poor sample preparation procedures.
Analysis of PFAS in Milk by LC-MS/MS
May 15th 2025Dairy milk is one commodity that can be impacted by environmental contaminants, such as PFAS, so it is important to implement extensive, robust, and accurate testing. In this work, a sensitive and reliable method was developed for the analysis of PFAS in milk by LC-MS/MS at levels as low as 0.01 µg/kg.
Columns & Lab Supplies for PFAS Analysis
May 15th 2025Finding suitable columns and products for PFAS analysis can be simplified using the product guide tables below, which detail the lab supplies for PFAS analysis that are appropriate for widely accepted test methods from around the world, including U.S. agencies (CDC, EPA, FDA, and USDA); European agencies (DIN); and international standards (ASTM and ISO).
