The National Center for Research Resources, a branch of the National Institutes of Health, has granted the University of Wisconsin- Madison a $1.6 million federal grant to purchase a mass spectrometer, a nuclear magnetic resonance spectrometer, and a liquid-chromatography system, integrated into a single instrument.
The National Center for Research Resources, a branch of the National Institutes of Health, has granted the University of Wisconsin- Madison a $1.6 million federal grant to purchase a mass spectrometer, a nuclear magnetic resonance spectrometer, and a liquid-chromatography system, integrated into a single instrument. The device will help the university search for new antibiotics and drugs and perform other research. UW-Madison is one of 20 universities that is receiving funding to purchase tools to help them stay at at the leading edge of research in biology and medicine.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.