The Application Notebook
The QC for the pharmaceutical industry is based on methods developed on a variety of columns. At Orochem, we have attempted to address method development utilizing unique chemistries such as the OROSIL C18 to analyze a wide range of acidic, basic, and neutral compounds. Data is presented on a few representative compounds and unique separation criteria with their associated chromatograms.
The QC for the pharmaceutical industry is based on methods developed on a variety of columns. At Orochem, we have attempted to address method development utilizing unique chemistries such as the OROSIL C18 to analyze a wide range of acidic, basic, and neutral compounds. Data is presented on a few representative compounds and unique separation criteria with their associated chromatograms.
Figure 1
We have successfully developed methods for more than 25 analytes with the Orosil C18 column. The OROSIL C18 chemistry provides a unique platform for the analytes currently targeted by the pharma industry towards major diseased states.
Orochem Technologies Inc,
Eisenhower Ln South, Lombard, IL 60148
Tel: 630-916-0225
Analyze Charge Variants in Antibody-Based Therapeutics Using Cation Exchange Chromatography
July 18th 2024This application note discusses the latest development on high performance cation exchange bio-separation columns for determining charge variants in protein-based biotherapeutics, as well as the strategy on method development.