Practical Aspects of Mucopolysaccharidoses Screening with Thin-Layer Chromatography

Author(s)Krishna Yanamandra, Benjamin Y. Lee, Theodore F. Thurmon

Scored layers, sequential development, modifications of the development chamber, and a careful choice of standards produce better reliability in thin-layer chromatography analysis of urine for the diagnosis of mucopolysaccharidoses. In equivocal cases, repeating the procedure and varying the solvents will improve results.

External Link - article-3014.pdf

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