Chromatographic conditions were developed for a fast GC-MS glycol ether analysis on the Rxi®-1301Sil MS column. This cyanobased thin film column provides better resolution and faster run times than the thick film cyanopropylphenyl-type columns commonly used for speciation of the glycol ethers. The glycol ethers are high production volume industrial chemicals that often occur as complex mixtures of isomers. The Rxi®-1301Sil MS column is uniquely matched for the separation of these isomers while still producing narrow and symmetric peaks for the low molecular weight ethylene glycol ethers.
Analyze Charge Variants in Antibody-Based Therapeutics Using Cation Exchange Chromatography
July 18th 2024This application note discusses the latest development on high performance cation exchange bio-separation columns for determining charge variants in protein-based biotherapeutics, as well as the strategy on method development.
The Power of HPLC/SFC Control and AQbD in One Software
July 17th 2024Download this infographic for a quick overview of Shimadzu’s LabSolutions Method Development (MD) software, an effective and automated software solution for U/HPLC method development that uses analytical quality by design (AQbD) principles in its workflow.