A group of researchers at the University of Nevada-Reno (Reno, Nevada), led by Dr. Jimi Francis, conducted a study, "Comparative Analysis of Nutrients in Baby Milk Using Varied Milk Delivery Systems." The study measured the level of nutrient loss using HPLC methods during simulated baby bottle feedings and has found that some bottle types resulted in significant loss of ascorbic acid (vitamin C) during a typical 20-min feeding.
A group of researchers at the University of Nevada-Reno (Reno, Nevada), led by Dr. Jimi Francis, conducted a study, "Comparative Analysis of Nutrients in Baby Milk Using Varied Milk Delivery Systems." The study measured the level of nutrient loss using HPLC methods during simulated baby bottle feedings and has found that some bottle types resulted in significant loss of ascorbic acid (vitamin C) during a typical 20-min feeding. The researchers examined human milk as well as two types of infant formula. The milks were delivered through seven different major brand baby bottles with five samples collected from each bottle: baseline, 5 min, 10 min, 15 min, and 20 min. Each sample was analyzed for vitamin C using normal-phase HPLC and each collection was completed in triplicate to ensure the consistency of results. The results suggest that the amount of air within a bottle, bottle design, and the impact on vitamin C levels warrant closer examination.
Study Explores Thin-Film Extraction of Biogenic Amines via HPLC-MS/MS
March 27th 2025Scientists from Tabriz University and the University of Tabriz explored cellulose acetate-UiO-66-COOH as an affordable coating sorbent for thin film extraction of biogenic amines from cheese and alcohol-free beverages using HPLC-MS/MS.
Multi-Step Preparative LC–MS Workflow for Peptide Purification
March 21st 2025This article introduces a multi-step preparative purification workflow for synthetic peptides using liquid chromatography–mass spectrometry (LC–MS). The process involves optimizing separation conditions, scaling-up, fractionating, and confirming purity and recovery, using a single LC–MS system. High purity and recovery rates for synthetic peptides such as parathormone (PTH) are achieved. The method allows efficient purification and accurate confirmation of peptide synthesis and is suitable for handling complex preparative purification tasks.