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John Dolan has been writing "LC Troubleshooting" for LCGC for over 25 years. One of the industry's most respected professionals, John is currently a principal instructor for LC Resources, Walnut Creek, California He is also a member of LCGC's editorial advisory board.
LCGC North America
Dolan examines some options for increasing the retention of polar compounds, which is a goal when using gradient elution scouting runs to screen the retention characteristics of compounds for separation by reversed-phase liquid chromatography.