News|Articles|October 31, 2024
Robust Oligonucleotide Molecular Weight Confirmation via LC/MS
Author(s)Agilent Technologies, Inc.
Oligonucleotides—therapeutic agents for difficult-to-treat diseases—rely on precise molecular weight confirmation to ensure quality during development. Experts from Agilent Technologies explore the challenges of liquid chromatography-mass spectrometry (LC/MS) analysis in oligonucleotide synthesis, as well as strategies for accurate deconvolution, method development, and optimal equipment selection.
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