Scaled Down EPA Methods 8270 and 625: Solid Phase Extraction of 100 mL Samples or Less
The EPA has updated methods 8270 (8270E) and 625 (625.1) to both now permit the use of solid phase extraction (SPE) to analyze for semi-volatile organic compounds (SVOCs) in aqueous samples and TCLP leachates. As a result of new advancements in instrumental sensitivity, smaller sample sizes can now be utilized to obtain required method detection limits, reducing solvent and standard consumptions and overall sample preparation time. This application note describes a reliable, efficient, and cost-effective SPE method utilizing two stacked cartridges for the extraction of 100 mL water samples or less.
Linking LC-HRMS Features to Aquatic Toxicity: A Nontargeted Approach Without Compound Identification
July 7th 2025A recent study conducted by the University of Amsterdam (Amsterdam, Netherlands) and the University of Queensland (Queensland, Australia) developed a novel prioritization strategy that directly links fragmentation and chromatographic data to aquatic toxicity categories, bypassing the need for identification of individual compounds. LCGC International spoke to Viktoriia Turkina of the University of Amsterdam, lead author of the paper that resulted from this study, about their work.
Detection and Risk Assessment of Mycotoxins in Commercial Tortillas Using HPLC-Based Methods
July 4th 2025A joint study between Selçuk University (Konya, Turkey) and Hitit University (Corum, Turkey) determined the natural occurrence and concentrations of the mycotoxins ochratoxin A (OTA) and deoxynivalenol (DON) in commercially available tortillas in Turkey. Contamination levels were quantified using validated analytical methods based on high-performance liquid chromatography (HPLC) coupled with fluorescence or ultraviolet detectors (HPLC-FLD or HPLC–UV).
