Seven Must Know Points to Understand Atmospheric Pressure Chemical Ionization

January 19, 2015

CHROMacademy delivers key knowledge quickly in bite-size modules, and to prove this here is our seven point guide to understanding atmospheric pressure chemical ionization.

 

 

CHROMacademy delivers key knowledge quickly in bite-size modules, and to prove this here is our seven point guide to understanding atmospheric pressure chemical ionization.

1) Atmospheric pressure chemical ionization (APCI) uses gas-phase ion-molecule reactions at atmospheric pressure. It relies on the formation of a plasma of ions comprised, mainly, from the HPLC mobile phase components.

2) In APCI the eluent is introduced into the interface using a capillary of similar design to the ESI source. However, no potential is applied to the capillary, instead the liquid emerges from the capillary surrounded by a flow of inert nebulizing gas into a heated, vaporizing region.

The complete article is available to CHROMacademy Lite and Premier members here >>

CHROMacademy Lite Membership is FREE and it only takes two minutes to register.

With a Lite Membership you are given access to:

  • This month's webcast & tutorial

  • Selected eLearning modules

  • Featured CHROMacademy Content

  • The CHROMacademy forum

Test drive CHROMacademy and check out more great content available FREE to our Lite members »