High-performance liquid chromatography (HPLC) confirms safe blood levels of slow-release bupivacaine nanoparticles.
|Articles|October 24, 2012
- The Column-10-24-2012
- Volume 8
- Issue 19
Taking Advantage of Sub-2μm Core-Shell Particles for Ultra-Fast and Efficient Urinary Excretion Profiling
Author(s)Simon Lomas, Jeff Layne
Urinary excretion profiling is a key element in the pharmokinetic characterization of new chemical entities (NCEs). Recent advances in ultra-high performance liquid chromatography (UHPLC) column technology offer improved results for liquid chromatography tandem mass spectrometry (LC–MS¬–MS) analysis, enabling rapid quantification of specific drugs and their metabolites in biological matrices.
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Urinary excretion profiling is a key element in the pharmokinetic characterization of new chemical entities (NCEs). Recent advances in ultra-high performance liquid chromatography (UHPLC) column technology offer improved results for liquid chromatography tandem mass spectrometry (LC–MS) analysis, enabling rapid quantification of specific drugs and their metabolites in biological matrices.
Articles in this issue
about 14 years ago
Holistics evidenceabout 14 years ago
Petrochemical Profilingabout 14 years ago
Lethal biteabout 14 years ago
Hydrogel deliveryabout 14 years ago
Fishing for antidotesabout 14 years ago
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