Supplementary Information: Non-aqueous Ion-Exchange Chromatography Using High Acid‑base Concentration: A Strategy for Purifying Non-crystalline Pharmaceutical Intermediates

The following document below includes the following supplementary information for the peer-reviewed article “Non-aqueous Ion-Exchange Chromatography Using High Acid‑base Concentration: A Strategy for Purifying Non-crystalline Pharmaceutical Intermediates” that was published in the March 2021 issue of LCGC Europe:

• The HPLC conditions
• Additional information on calculations, including the milligram to multigram scale calculations and the multigram to multikilogram calculations
• Table A: Physical and chemical properties of the selected cation exchange resin
• Table B: Experimental details and scaling