Mass spectrometry (MS) is considered to be the gold standard in chemical detection due to the speed, selectivity, sensitivity, and versatility of the method. A miniaturized, linear ion trap, mass spectrometer can rapidly detect and unequivocally identify chemical targets that reduce the cost to analyze field samples and, more importantly, eliminate gaps in security because actionable information can be obtained on timescales that are relevant for security personnel
Fundamentals of Benchtop GC–MS Data Analysis and Terminology
April 5th 2025In this installment, we will review the fundamental terminology and data analysis principles in benchtop GC–MS. We will compare the three modes of analysis—full scan, extracted ion chromatograms, and selected ion monitoring—and see how each is used for quantitative and quantitative analysis.
Characterizing Plant Polysaccharides Using Size-Exclusion Chromatography
April 4th 2025With green chemistry becoming more standardized, Leena Pitkänen of Aalto University analyzed how useful size-exclusion chromatography (SEC) and asymmetric flow field-flow fractionation (AF4) could be in characterizing plant polysaccharides.
This information is supplementary to the article “Accelerating Monoclonal Antibody Quality Control: The Role of LC–MS in Upstream Bioprocessing”, which was published in the May 2025 issue of Current Trends in Mass Spectrometry.