CA Agilent
|Articles|March 1, 2004

LCGC Europe

  • LCGC Europe-03-01-2004
  • Volume 17
  • Issue 3

In-Tube Solid-Phase Microextraction and On-Line Coupling with High-Resolution GC

A novel device for coupling on-line in-tube SPME with capillary GC is presented by the guest authors and the method's application demonstrated for the analysis of contaminants in water.

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Figure 2. Split injection used to measure triplicate test of MTBE, hexane, o-xylene, and 1-methylnaphthalene comparing different solvents (methanol, methylene chloride) and column insertion distances starting with 0.5 mm, 5.0 mm, 10.0 mm, 15 mm, and 20.0 mm. Methanol had the best performance at the 5.0 mm insertion distance and methylene chloride looked slightly better at the 0.5 mm. We would still recommend not going below the 5.0 mm manufacturer recommended insertion distance.
Revisiting insertion distance for methanol and methylene chloride in GC analysis and confirming that insertion depth strongly affects response and reproducibility.