Column: Sample Prep Perspectives

“Sample Prep Perspectives” keeps you up to date on new developments in sample preparation and provides practical tips to improve the effectiveness and ease of your sample preparation processes. Columnist Douglas E. Raynie is a department head and associate research professor at South Dakota State University. His research interests include green chemistry, alternative solvents, sample preparation, high resolution chromatography, and bioprocessing in supercritical fluids.

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The QuEChERSER Mega-Method

January 01, 2022

QuEChERS has been updated to suit modern instrumentation. Now also “efficient and robust,” QuEChERSER is a “mega-method” that covers a wider polarity range.

Putting the Sample into Sample Preparation

November 01, 2021

We explore the aspects of sampling that are of highest importance in an analytical scheme. Devices and processes for obtaining appropriate samples outside of the laboratory are presented.

Origins of Sample Preparation Technologies

September 01, 2021

We look at five modern treatments of chromatographic sample extraction, explaining their initial conception and development to shed light on their current roles as analytical tools.

Heroic Failures in Sample Preparation

July 01, 2021

These seven case studies capture and expand on lessons presented at ChromTalks.

New Sample Prep Products and Accessories

May 01, 2021

We assess the landscape of new sample preparation instrumentation, supplies, and accessories introduced over the past 12 months.

Next-Generation Sorbent-Based Extractions with Metal-Organic Frameworks

March 01, 2021

Sorbent-based extractions using metal-organic frameworks (MOFs) have several advantages, notably selectivity. How do these extractions work, and where are they most useful? We look into the current state of the art.

Turning Up the Heat: The Effect of Temperature on Analytical Extractions

January 01, 2021

Temperature is frequently employed to enhance analytical extractions, especially with solid samples or volatile analytes. Using temperature to enhance analytical extractions continues today with more recently developed techniques, which we explore.

Electromembrane Extraction with Vials of Conducting Polymer

August 01, 2020

In electromembrane extraction (EME), the target analyte is extracted from an aqueous sample across a supported liquid membrane (SLM) and analyzed using LC. Through the study presented here, we demonstrate the principles of the technique and test its performance.

LCGC North America

New Sample Preparation Products and Accessories

May 01, 2020

Our annual review of the new sample preparation instrumentation products introduced in the past year.

LCGC North America

Sample Preparation in the Rearview Mirror: Looking Back on 2019

March 01, 2020

This selection of influential recent papers on chromatographic sample preparation gives us a sense of important developments.