The Use of Micrometer-Sized Particles in Ultrahigh Pressure Liquid Chromatography

TRLC can obtain separations similar to those of reversed-phase LC while using only water as the mobile phase.

The application of porous layer open tubular (PLOT) columns can be expanded beyond light compounds to separations of analytes with heavier boiling points.

At HPLC 2022, we heard about new research and developments, in areas such as column technologies, portable instrumentation, and machine learning, among others.

With a new prototype, we explore how to improve the resolution power and usability of LC–MS instruments for routine analysis in pharmaceutical applications.

Knowing the variables that most affect the sample loading capacity in a porous layer open tubular (PLOT) column is vital to determining how much sample to inject.

Our yearly report on liquid chromatography (LC) columns and accessories commercially released over the past year.