News|Webcasts|July 22, 2024

What GC-MS Operators Need to Know

Webinar Date/Time: Thurs Aug 15, 2024 2pm EDT

Join our webcast to master GC-MS techniques, from sample prep and ionization to mass analysis, tuning reports, and data interpretation.

Register Free: https://www.chromacademy.com/channels/gc-ms/technique/what-gc-ms-operators-need-to-know/?sti=mjh

Event Overview:

This informative webcast discusses special GC considerations, how analyte ionization works, and the principles of mass analysis using quadrupole devices. We will show you how to interpret an MS tune report, the power of various MS operating modes, and how to process and understand the data you generate. This essential information will allow you to better implement this technique successfully in your laboratory.

Topics include:

•Essential sample preparation troubleshooting strategies

•Why do we use MS detectors with GC?

•Vacuum – don’t be scared!

•What special GC considerations are there when working with MS detectors

•Setting GC acquisition parameters

•Electron ionization (EI) and chemical ionization (CI)

•Quadrupole mass analyzers

•Understanding tune reports

•Setting MS acquisition parameters

•Understanding GC-MS data

Register Free: https://www.chromacademy.com/channels/gc-ms/technique/what-gc-ms-operators-need-to-know/?sti=mjh


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Figure 2. Split injection used to measure triplicate test of MTBE, hexane, o-xylene, and 1-methylnaphthalene comparing different solvents (methanol, methylene chloride) and column insertion distances starting with 0.5 mm, 5.0 mm, 10.0 mm, 15 mm, and 20.0 mm. Methanol had the best performance at the 5.0 mm insertion distance and methylene chloride looked slightly better at the 0.5 mm. We would still recommend not going below the 5.0 mm manufacturer recommended insertion distance.
Revisiting insertion distance for methanol and methylene chloride in GC analysis and confirming that insertion depth strongly affects response and reproducibility.