Application Notes: Biopharmaceuticals

Application Note: Electrochemical Reduction of Biopharmaceuticals

November 16, 2021

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With a new electrochemical cell, complete reduction of inter- and intra-disulfide bonds in mAbs is achieved. For cystine knots peptides, the sequence coverage was 100%.

Complementary Analysis with a 2D-LC–MS Instrument for Flexible Operation

November 08, 2021

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This goal of this note is identity confirmation of protein-based impurities of a therapeutic protein by multi heart-cut 2D-LC–MS in a top-down experiment.

App Note: Optimizing Control of Pump-Related Processes

October 25, 2021

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This white paper will illustrate how integrated pump controllers optimize pump performance by automatically controlling flow or pressure.

Application Note: Optimizing Control of Pump-Related Processes

October 05, 2021

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This white paper will illustrate how integrated pump controllers optimize pump performance by automatically controlling flow or pressure.

Optimizing Control of Pump-Related Processes

September 28, 2021

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This white paper will illustrate how integrated pump controllers optimize pump performance by automatically controlling flow or pressure.

Electrochemical Reduction of Biopharmaceuticals

September 27, 2021

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With a new electrochemical cell, complete reduction of inter- and intra-disulfide bonds in mAbs is achieved with superior sequence coverage.

HILIC Analysis for Polar Modifications of Proteins and Peptides

September 24, 2021

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Learn the advantages of HILIC to measure and monitor glycosylation, deamidation, and oxidation, which are critical for the function and form of proteins and peptides.

Adding MALS to Preparative IEC

August 31, 2021

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Multi-angle light scattering couples inline with ion exchange chromatography to estimate the aggregate content of protein fractions without additional offline assays.

Targeted Small Protein Analysis with a Single Quadrupole Mass Detector

August 25, 2021

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This tech note demonstrates the benefits of single quadrupole mass detection for small protein analysis.

Application Note: AAV Application Notebook

August 18, 2021

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AAV characterization and stability screening are achieved with multi-angle light scattering coupled to separation methods and high-throughput dynamic light scattering.