Application Notes: Biopharmaceuticals
Purification of Crude Samples in Drug Discovery
This application describes the purification of paracetamol from a crude sample in early-stage drug discovery. Outstanding purity (>99%) and recovery (>95%) are achieved.
SFC/UHPLC Separation of Pharmaceutical Impurities
This application note describes the improved identification of pharmaceutical low-level impurities when using SFC and UHPLC as orthogonal separation modes.
Quantitation of Chemical-Induced Deamidation and Oxidation on Monoclonal Antibodies
Dans cette note d’application vous découvrirez le QTof 6545XT et le logiciel BioConfirm 10.0 pour l’identification et la quantification des modifications post traductionnelles.
Brochure Analyse des N-Glycan libres
Cette brochure explique comment Agilent prend en charge l'ensemble du flux de travail des glycans de la préparation des échantillons à l'analyse LC, FLD, MS, et CE.
Sensitive Native Mass Spectrometry of Macromolecules Using Standard Flow LC–MS
Téléchargez cette application pour connaître notre solution à la caractérisation de protéine native complexe non covalent par HPLC SEC–MS : Application aux mAb, ADC, et complexes protéiques.
Compendium Caractérisation des attributs de qualité critiques du NIST mAb
Ce compendium couvre les techniques analytiques utilisées dans l’identification et la quantification des attributs de qualité critiques sur l’exemple de l’anticorps monoclonal NIST.
ROXY™ Exceed: A New Dedicated Potentiostat for Electrochemistry-MS
Mass Spectrometric Characterization of the Glycoform Peaks Separated by a Novel FcR Analytical Column
This application demonstrates the efficacy of this chromatographic technique for a fast orthogonal analysis to evaluate mAb ADCC activity.
Learn more about our HPLC-QTOF solution for the identification and quantification of post-translational changes for the development of therapeutic antibodies.
N-Glycan Analysis Brochure
In this applications resource you'll know how Agilent supports your entire released glycan workflow from sample preparation to LC-FLD–MS and CE analysis.