ASMS 2023 HDX-MS with Inline Electrochemical Reduction of Disulfide Bonds: State-of-the-Art
August 2nd 2023HDX-MS with online EC reduction enables successful epitope mapping of mAbs to challenging S-S bonded protein targets, e.g., VEGF. The biophysical characterization of VHH-IR4, a BBB-crossing single-domain antibody (sdAb) is described for the first time and was only possible using EC reduction.
ASMS 2023 SweetSep™ a New HPLC Column for the Fast Analysis of Carbohydrates and Glycans by LC-MS
August 2nd 2023High-Performance Anion Exchange Chromatography in combination with PAD or MS detection is the method of choice for the analysis of all classes of carbohydrates including glycans. A novel anion-exchange stationary phase SweetSep™ has been developed that allows for fast and high resolution separation.
HPLC 2023 Analysis of Carbohydrates in Food Using a New Anion Exchange Column SweetSep™ AEX200
August 2nd 2023The AEX200 column demonstrate (a) fast separation of mono-, di- and trisaccharides in various food sample matrices, (b)sensitive quantification of carbohydrates down to femtomole levels, (c) high-resolution separation of high-molecular weight oligosaccharides with a degree of polymerization up DP of 60.
HPLC 2023 New Anion-Exchange Columns for the Analysis of N-Glycans Using HPAEC-PAD/MS
August 2nd 2023Separation of all 6 glycan monosaccharides of interest and 2-Deoxy-D-Glucose (glycosylation inhibitor) was achieved within 7 minutes using the new SweetSep™ AEX20 column under isocratic elution conditions. Furthermore, profiling of released N-glycans from glycoproteins without the need for sample derivatization is shown using HPAEC-MS.
The Future of Mass Spectrometry
August 24th 2022Wednesday August 24, 2022 at 10am ET | 3pm BST | 4pm CEST Join us for this virtual symposium as we explore the future of mass spectrometry (MS) technology. Technical talks from scientists at leading mass spectrometry instrument manufacturers will bring you up to date on important developments, including many announced at the ASMS 2022 event. They will explain and demonstrate the technologies underlying advanced capabilities of mass spectrometry techniques and instruments, addressing how those capabilities can translate into performance improvements such as increased sensitivity, greater robustness, and ease-of-use.
Improved Electrochemical Detection for HPLC – Easy and Affordable
November 4th 2021Thursday, November 4, 2021 at 11am EDT | 8am PDT | 3pm GMT | 4pm CET HPLC with state-of-the-art electrochemical detection, the most sensitive and affordable detection technique. Learn about the tremendous power of Electrochemical Detection!