Hamilton Company

Cells beyond their sell-by date exhibit a higher probability to propagate damaged cellular components like DNA, which leads to disease. It is therefore necessary for the body to remove these old malfunctioning cells, which can be done with garlic. All of the active components of garlic are easily isolated using the 5 µm PRP-C18 HPLC column.

Capsaicin, the compound responsible for the burning sensation in chili peppers, has been researched for its potential therapeutic benefits, including reducing cholesterol and blood sugar levels, and exhibiting anti-inflammatory and analgesic properties. Hamilton's PRP-C18 reversed-phase HPLC column was used to isolate major capsaicinoids, with formic acid as the aqueous mobile phase, achieving good correlation with literature values at 10190 Scoville Heat Units. The Hamilton PRP-C18 column demonstrated excellent peak shape and can be easily regenerated, making it an indispensable tool for synthetic chemists.

In this study of an essential oil, we have developed an HPLC method for the separation of 6 well-known markers for the determination of purity of Ylang-Ylang oil.

Due to the short half-life of the 18F radionuclide, radiotracers are preferably produced locally or transported over short distances, leading to local production. On-site quality control is critical before clinical use. See how the RCX-10 enables reliable analysis for radiotracers.

This study analyzed BPA and its derivatives leaching from BPA-free polycarbonate water bottles using HPLC with UV detection and found that these bottles still contain bisphenol derivatives that can leach into water or ethanol. Leaching increased with temperature and was more pronounced with ethanol than hot water. Repeated washing with either hot water or 40% ethanol effectively removed leachable bisphenols without damaging the bottles.

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Identification of polyphenolic catechin compounds for health and industrial quantification and quality control of tea products.

GRPC peptides are found in the entire body. Isolation of seven classic GRPC peptides initiating in the GI tract could implicate disease.

The diterpenoid, paclitaxel, which was identified as a potent chemotherapy agent for breast and ovarian cancer originates from the Pacific Yew tree. The isolation of paclitaxel from its major impurities is shown with the use of Hamilton’s PRP-1 (5 µm) HPLC column.

The identification benzodiazepine metabolites can be highly valuable in detecting abuse. Metabolites of oxazepam are found containing both hydroxyl and glucuronides.

Plasticizers added to water bottles to add stability to the bottles can be unknowingly extracted in drinks leading to possible endocrine interactions.

The fast identification of tocopherols are important for various applications including free radical scavenging for human health and food stuff preservation.

Isolation of capsaicin for medicinal uses is easily achieved with the PRP-C18 RP-HPLC resin.

Discover how the HC-75 series uses a ligand exchange mechanism in order to interact more or less strongly with the analytes of interest.

This brief communitation hightlights the assessment of Hamilton PRP-3 HPLC column attributes when analyzing biologically active peptides.

Hamilton has produced a series of reference guides to assist science professionals in finding the best-suited products and configurations for their applications. The Syringe and Needle Reference Guide provides detailed information on Hamilton Company’s full portfolio of syringes and needles. Everything from cleaning and preventative maintenance to individual part numbers are available for review. It also includes selection charts to help you choose between syringe terminations like cemented needles and luer tips.

Magic mushrooms, once taboo, have recently experienced a renaissance. This new awakening is partially due to new findings that indicate the effects of psilocybin, and its dephosphorylated cousin psilocin may produce long lasting results for patients who might be struggling with anxiety, depression, alcohol and drug abuse, and post-traumatic stress disorder. Hamilton Company has developed a methodology for the isolation and identification of 5 common psychedelic compounds used in the potential treatment of disease. The PRP-1 HPLC column resin remains stable in the harsh alkaline conditions ideal for better separations.

Top quality materials and skilled workmanship ensure Hamilton syringes consistently deliver the highest possible performance for reliable analyses. With proper care and handling, Hamilton syringes provide unsurpassed performance year after year. This guide covers daily syringe use along with safety information and troubleshooting tips.

The G protein-coupled receptors (GPCR) are found throughout the entire body and have shown significance in the development of new therapeutic treatments. Isolation of seven classic GRPC peptides initiating in the GI tract highlights the benefits of using the polymer-based PRP-3, a reversed-phase resin. The covalent bonds found in the PRP-3 exhibit advantageous interactions between the biological π bonds found in the peptides and the available aromatic benzyl rings of the resin.

The diterpenoid, paclitaxel, which was identified as a potent chemotherapy agent for breast and ovarian cancer originates from the Pacific Yew tree. The isolation of paclitaxel from its major impurities is shown with the use of Hamilton’s PRP-1 (5 µm) HPLC column.

Garlic has been found to exhibit a multitude of proliferative health benefits in the realm of cardiac events.

A reversed-phase HPLC method was developed to separate five steroid hormones, with partition coefficients ranging from 1.47 (cortisone) to 4.5 (pregnenolone).

Sulfide compounds found in garlic oils are used in therapeutics and prophylaxis of certain cancers, and are prevalent in cell health.

Identification of the five most common saccharides found in packaged foods, lactose, maltose, sucrose, fructose, and glucose, is easily resolved on the RCX-30 column.

The Raffinose Family of Oligosaccharides (RFO) is comprised of low molecular weight non-reducing sugars. Analysis of these compounds is not easily done unless using HC-75.

Isolation of six common allergens can be achieved by utilizing reversed-phase HPLC using an alkaline eluent.

With the growing utility of the K vitamin series of molecules, a need appears relevant for both food labeling of constituents and for research based separation of the natural and synthetic compounds of vitamin K. The fast simple method developed by Hamilton Company using the PRP-C18 column allows for simple efficient identification of the whole vitamin series (K2, K3, and K4).

This brief communication highlights the assessment of Hamilton PRP-3 HPLC column attributes when analyzing biologically active peptides.

Despite the utility of the essential oil mixture, it has been shown that allergies can arise from some of the individual components.