
UCT’s Refine™ Ultra-Filtration Technology allows for sample precipitation and filtration to occur simultaneously in the individual column or well.

UCT’s Refine™ Ultra-Filtration Technology allows for sample precipitation and filtration to occur simultaneously in the individual column or well.

This method outlines a modified QuEChERS based procedure that has been optimized to extract various drug compounds from liver prior to analysis by LC–MS.

UCT’s Refine™ Ultra-Filtration Technology allows for sample precipitation and filtration to occur simultaneously in the individual column or well.

Describes the highly retentive, universal nature of UCT’s polymeric Styre Screen® HLD sorbent for the analysis of acidic, neutral, and basic compounds in blood and urine.

This method outlines a modified QuEChERS based procedure that has been optimized to extract various drug compounds from liver prior to analysis by LC–MS.

Outlines a simple three-step method for the extraction of Loperamide and its main metabolite, N-desmethyl Loperamide, from blood using Clean Screen® XCEL SPE|columns.

This application describes an easy, fast, and effective method using QuEChERS for the quantitative analysis of benzodiazepines in whole blood.

This application describes an easy, fast, and effective method using QuEChERS for the quantitative analysis of benzodiazepines in whole blood.

This featured application note exploits the highly retentive, universal nature of UCT’s polymeric Styre Screen® HLD sorbent for the analysis of acidic, neutral, and basic compounds in blood and urine.

This application note details two UCT sample preparation approaches (SPE and QuEChERS) that can be used for the extraction and clean-up of mycotoxins from grain-based food.


This application note effectively outlines a simple three-step method for the extraction of loperamide and its main metabolite, N-desmethyl loperamide, from blood.






This application note describes the development of an analytical method for the sensitive and accurate determination of free and total thyroid hormones in serum and plasma using a mixed-mode SPE extraction procedure and UHPLC–MS-MS analysis.

Since their beginnings in 1986, UCT has evolved into a major competitor in the field of silica based solid phase extraction technology. The first to pioneer commercially available ‘mixed-mode’ SPE products, 30 years later UCT is still optimizing sample analysis for forensic, pharmaceutical, clinical, environmental and agricultural laboratories. Michael J. Telepchak, founder and CEO UCT, Inc., has laid the foundation for this powerful technology and has truly served as a catalyst for its transformation from a novel technique to an industry gold standard. From fundamental chemistry to manufacturing and business development, he has bared witness to all facets of the evolution of solid phase extraction and will speak on the monumental impact it has made on the scientific community.

The use of ion-exchange sorbents for the preconcentration, separation and determination of metal ions is well established in the literature. Selection of an appropriate sorbent ensures both high efficiency in metal chelating while minimizing the mass of sorbent required for a particular analytical task. A high efficiency sorbent means that a smaller bed mass may be used thereby reducing the quantity of solvent required for elution yielding greater analytical sensitivity.

The use of ion-exchange sorbents for the preconcentration, separation and determination of metal ions is well established in the literature. Selection of an appropriate sorbent ensures both high efficiency in metal chelating while minimizing the mass of sorbent required for a particular analytical task. A high efficiency sorbent means that a smaller bed mass may be used thereby reducing the quantity of solvent required for elution yielding greater analytical sensitivity.

This application outlines a simple, fast, and cost-effective method for the determination of 34 multi-class pesticides, including one of the most problematic pesticides, pymetrozine in blueberries.

This application utilizes the original, non-buffered QuEChERS (acronym for quick, easy, cheap, effective, rugged, and safe) technique to quantify anabolic steroids in human whole blood

Organochlorine (OC) pesticides are hydrocarbons with multiple chlorine substitutions primarily used as insecticides. OC pesticides do not break down easily as the chlorine-carbon bonds are very strong.


EPA is updating method 525.2. The CCL3 includes 104 analytes. UCT has evaluated the recoveries of these compounds, including the current list, using proposed changes to the method with the C18-based UCT ENVIRO-CLEAN? 83 mL Extraction Cartridge ECUNI525.