The Application Notebook-09-01-2010

The Application Notebook

An Accurate and Robust LC–MS Method for the Identification of Illicit Drug Salt Forms

September 01, 2010

General

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Illicit cocaine, amphetamine, methamphetamine, and ecstasy (MDMA) are often encountered in the form of salts and identification of the specific counter ion present may provide valuable information about the source of production and the manufacturing pathway.

Nitrosamines in Drinking Water

September 01, 2010

Environmental

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N-Nitrosodimethylamine and other structurally similar nitrosamines are classified as probable carcinogens by the U.S. EPA, and their presence has been reported in California drinking water since 1998.

Next-Generation Autosampler for LC–MS Equipped with Straight Injection TechnologyTM

September 01, 2010

General

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This article reports a new sample injection mechanism for an autosampler that directly transfers a sample to column without passing it through any flow-changing device, and hence minimizes a delay volume and reduces a carryover signal to the extreme level.

The Application Notebook: A More Critical Resource Than Ever

September 01, 2010

From the Publisher

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To the members of LCGC's readership, the science behind the headlines is always apparent. Separation science in general, and chromatography in particular, find application in nearly every facet of everyday life, from pharmaceutical analysis to the biomedical field to environmental testing, and this Application Notebook is a tribute to just how thoroughly separation science permeates our daily lives.

Increasing Proteome Coverage with ETD and CID in One Run Using Intelligent Data-Dependent Decision Tree Logic

September 01, 2010

Biological

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Since the addition of electron transfer dissociation (ETD) to the Thermo Scientific LTQ Orbitrap hybrid mass spectrometers, ETD has become a standard tool for proteomics research together with the traditional collision-induced dissociation (CID) (1).

Extend UHPLC Column Lifetime with KrudKatcherTM Ultra In-Line Filters

September 01, 2010

General

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For many years, the use of guard columns has been advocated by column manufacturers and other experts to protect and extend column lifetime and performance of analytical columns from potential damage caused by the presence of chemical contaminants and microparticulates in the sample and mobile phase.

Vol 28 No 9 LCGC North America September 2010 Application Notebook PDF

September 01, 2010

Issue PDF

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Click the title above to open the LCGC North America September 2010 Application Notebook, Vol 28 No s9, in an interactive PDF format.